September 10th 2024
The endocrinology month in review for August 2024 spotlights 6 pieces of major pipeline news or regulatory announcements as well as multiple episodes of Diabetes Dialogue.
Scientists Map Out Genetic Hot Spots for Diabetes
February 17th 2010Researchers have built the first high-resolution atlas of regulatory elements in the most studied cell type for treatment and prevention of type II diabetes, guiding scientists to regions of the genome that appear functionally relevant.
American Association of Clinical Endocrinologists Approves New Diagnosis for Diabetes
February 2nd 2010The guidelines incorporate the use of A1c as an additional diagnostic criterion for type 2 diabetes. An A1c of 6.5 or greater is now considered an alternate criterion for the diagnosis of type 2 diabetes.
Beta Cells Need Key Protein to Divide and Conquer Diabetes
January 27th 2010Researchers at Joslin Diabetes Center have identified a cell-cycle protein essential for beta-cell replication to respond successfully to insulin resistance. The finding may point toward eventual therapies for preventing or treating type 2 diabetes.
Stress Peptide and Receptor May Have Role in Diabetes
January 22nd 2010Researchers at the Salk Institute for Biological Studies have found that the neuropeptide corticotropin-releasing factor also plays a part in the pancreas, where it increases insulin secretion and promotes the division of the insulin-producing beta cells.
Insulin Pumps Might Have Slight Advantage in Type 1 Diabetes
January 18th 2010A meta analysis found that participants using insulin pumps had significantly lower HbA1c levels than those using multiple daily injections, though no differences existed between the two for non-severe low blood glucose levels.
A1C Test Given Prominent Role in 2010 ADA Diabetes Screening Guidelines
December 30th 2009In the current Revisions to the Standards of Medical Care in Diabetes, the section on Diagnosis of Diabetes has been revised to include the use of A1C to diagnose diabetes, with a cut-point of 6.5 percent or greater.
Study Identifies Genetic Predeterminants for Diabetes in African-Americans
December 29th 2009RNA and DNA analyses of blood samples taken from patients undergoing treatment in the cardiac catheterization lab at the University of North Carolina identified the existence of variations in glucose metabolizing genes that might lead to health-related differences in these racially distinct patient groups.
Relieving Stress on Insulin-producing Cells May Prevent Diabetes
December 28th 2009Scientists at Joslin Diabetes Center have found that a relatively little-studied enzyme plays a central role in defending beta cells against oxidants, but is damaged by the high levels of blood glucose produced in diabetes.