Type 2 Diabetes

This advisory finds that data are inconclusive on heart risks associated with diabetes medications, but also notes that patients taking these drugs should be closely monitored by their healthcare providers.

In a recent study, gastric banding proved to be a more effective intervention than intensive lifestyle management, leading to a substantial and durable reduction in obesity and to better health.

Researchers have built the first high-resolution atlas of regulatory elements in the most studied cell type for treatment and prevention of type II diabetes, guiding scientists to regions of the genome that appear functionally relevant.

Type 2 diabetics with silent cerebral infarction are more than twice as likely to develop or die from end-stage kidney disease.

While a doctor is often concerned about a patient's risk of long-term complications from high or uncontrolled blood sugar, the patient might have more pressing issues, such as back pain or depression.

The guidelines incorporate the use of A1c as an additional diagnostic criterion for type 2 diabetes. An A1c of 6.5 or greater is now considered an alternate criterion for the diagnosis of type 2 diabetes.

Recent study results indicate that when an individual has more energy available, they tend to be more future-oriented, and therefore will engage in better decision making.

Researchers at Joslin Diabetes Center have identified a cell-cycle protein essential for beta-cell replication to respond successfully to insulin resistance. The finding may point toward eventual therapies for preventing or treating type 2 diabetes.

Once-daily human GLP-1 analog indicated as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

JDRF to provide $8 million in funding for three years, targeting the creation of a system ready for FDA review within four years.

Researchers at the Salk Institute for Biological Studies have found that the neuropeptide corticotropin-releasing factor also plays a part in the pancreas, where it increases insulin secretion and promotes the division of the insulin-producing beta cells.

The identification of new genetic markers and variants that are related to type 2 diabetes may lead to new diagnostic and treatment options.

A meta analysis found that participants using insulin pumps had significantly lower HbA1c levels than those using multiple daily injections, though no differences existed between the two for non-severe low blood glucose levels.

Risk factors such as high cholesterol, diabetes and high blood pressure are being found at an earlier age for survivors of pediatric cancer than in the general population.

Diabetes treatment typically requires multiple medications, meaning beneficiaries with diabetes are likely to reach the doughnut hole sooner than are those who do not have chronic diseases.

University of Pennsylvania researchers are testing whether people with a lower body mass index may benefit from surgery to treat type 2 diabetes, high blood pressure or other significant health problems.

A University of Chicago study study confirms that undiagnosed OSA is very common among patients with type 2 diabetes, indicating that it is a largely unrecognized additional medical risk factor in these patients.

It looks like 2010 is starting off with some changes in healthcare on the horizon – from a number of angles.

In the current Revisions to the Standards of Medical Care in Diabetes, the section on Diagnosis of Diabetes has been revised to include the use of A1C to diagnose diabetes, with a cut-point of 6.5 percent or greater.

Researchers have found that so-called "good cholesterol" (high-density lipoprotein, or HDL), has less heart-protective and blood vessel-protective effects in people with type 2 diabetes.

RNA and DNA analyses of blood samples taken from patients undergoing treatment in the cardiac catheterization lab at the University of North Carolina identified the existence of variations in glucose metabolizing genes that might lead to health-related differences in these racially distinct patient groups.

South Dakota State University has demonstrated that a culturally based nutrition intervention can promote small, but beneficial, changes in weight among Native Americans.

New evidence suggests that steroids could improve vision outcomes from diabetic macular edema, but that steroids were not superior to laser treatments for DME.

Scientists at Joslin Diabetes Center have found that a relatively little-studied enzyme plays a central role in defending beta cells against oxidants, but is damaged by the high levels of blood glucose produced in diabetes.

Participants in a clinical trial attended weekly sessions to learn about the potential benefits of low-glycemic-index foods. After nine weeks, they had adopted a lower glycemic-index diet and recorded lower weight, smaller waists, and improved blood sugar levels.

Parental concerns and the willingness to adopt mobile-phone-based technology are likely tied to the unmet need of parents, including provider access, limited available information and support, and the complex management of children with diabetes.

Diabetics may have more difficulty accessing nutritious foods than those without the health condition, leading to unhealthy lifestyle choices, say Canadian researchers.

An additional cup of coffee consumed in a day was associated with a 7 percent reduction in the excess risk of diabetes according to the findings of meta analysis of studies examining coffee and tea consumption and diabetes risk.

Researchers at UT Southwestern and 14 other centers worldwide found that injections of the drug used to treat autoimmune disorders slowed beta cell destruction in the pancreas of those newly diagnosed with type 1 diabetes for at least a year.

Some neurologic disorders increase the risk of problematic outcomes of pregnancy. Data on such associations have been scant, but this is beginning to change. For example, with regard to epilepsy, there are a number of pregnancy registries which track outcomes related to antiepileptic drug therapy. However, large trials and population studies are not common.