Type 2 Diabetes

Individuals with mild to moderate coronary heart disease, treated with intensive medical therapy alone, were no more likely to die from a heart problem after five years than those who also had an angioplasty procedure.

Insulin resistance may affect long-term cardiovascular outcomes in type 1 diabetes and results indicate that insulin resistance is directly related to decreased heart and vessel function and appears to impair capacity to exercise.

Glucose intolerance during pregnancy predicts an increased likelihood of postpartum metabolic syndrome. In turn, cardiovascular risk factors at three months postpartum indicates that risk factors may be longstanding and contribute to long-term risk of cardiovascular disease.

New research indicates that the number of Americans living with diabetes will top 44 million by 2034, more than three times the number predicted in a 1991 study.

A New York Health Department report recognizes that citywide, the diabetes rate significantly exceeds the national rate and estimates that 200,000 New Yorkers have undiagnosed diabetes.

The Diabetes Surgery Summit position statement promotes the legitimacy of gastrointestinal surgery as a dedicated treatment for type 2 diabetes in carefully selected patients.

Taking a systems biology approach, UC San Diego researchers uncovered previously unknown effects of TZDs and insights that could lead to improved drug therapies for insulin resistance.

Joslin Diabetes Center research implicates the glucokinase/BAD complex in the death of beta cells when the insulin signaling pathway breaks down, and demonstrates that this mechanism is triggered in humans with type 2 diabetes.

More than half (62.4%) of US adults with type 2 diabetes were found to be obese, and 20.7% are morbidly obese. Among African-Americans with type 2 diabetes, one out of three are morbidly obese.

The Highmark Foundation released a report detailing the impact of more than $1.6 million in grants that it issued on diabetes care and services for Pennsylvanians.

A $1.8 million grant will help the University of Michigan investigate the use of herpes simplex virus-based vectors to deliver genes to sensory nerves from application in the skin, which researchers believe hold promise not only for the treatment of pain but also ultimately for the treatment of peripheral neuropathy itself.

The Diabetes Prevention Program Outcomes Study finds that moderate health improvements such as modest weight loss or the use of anti-diabetic drugs can prevent or lower the incidence of type 2 diabetes in high risk populations.

Researchers traced a molecular cascade that ends up increasing the expression of a novel target, the protein SHP-1, which de-activates PDGF activity and thus triggers cell death.

A recent study from Kaiser Permanente shows that women with diabetes face a 26% greater risk of also developing atrial fibrillation.

Heme, the protein responsible for making blood red, also helps maintain proper metabolism in the body, making its regulation relevant to the treatment of several diseases including obesity and diabetes.

The Insulin Receptor Substrate 1 Gene controls the body's response to insulin already in the bloodstream.

Making the transition from outpatient to inpatient has been thankfully only a slightly “bumpy” road, but it is amazing looking back on how our approach to inpatient diabetes care and hyperglycemia on the whole has changed over the past 10 years.

The chronic nature of the disease does not correlate to education or motivation when it comes to proper nutrition. Upwards of 85 percent of Look AHEAD trial participants exceeded recommended daily intake allowances.

"The Vine that Ate the South" may one day be known as "The Vine that Fought the Metabolic Syndrome," according to University of Alabama at Birmingham researchers.

Macrophages taken from vitamin-D-deficient diabetics were more likely to become foam cells, one of the earliest markers of atherosclerosis.

A few months ago the FDA issued a formal statement about the issue of sharing insulin pens and cartridges. In short, they gave it a big NO all around.

Due to results that could mask significant hypoglycemia or prompt excessive insulin use, diabetics should never use GDH-PQQ glucose meters or test strips while using drug products or therapies that contain certain sugars other than glucose.

New research based on transplanting Islets of Langerhan cells onto the anterior chamber of the mouse eye may pave the way for new diabetes treatment.

The Food and Drug Administration approved the Bristol-Myers/AstraZeneca once-daily drug Onglyza for the treatment of Type 2 diabetes in adults.

New research shows that the rates of serious complications among individuals with type 1 diabetes appear lower than reported historically, especially when patients are treated intensively.

When humanin was injected into the brains of diabetic rats, “the infused humanin significantly improved overall insulin sensitivity, both in the liver and in skeletal muscle,” according to the researchers.

At the time of my writing this blog, Sonya Sotomayor is being questioned (still) as part of her hearing prior to possibly being confirmed as a US supreme court Justice.

Researchers at Monash University in Australia have discovered a protein that is a "key link" between obesity and the onset of type 2 diabetes.

New research shows that Web-based intervention in the treatment of diabetes results in "significantly better" outcomes for patients.