The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
OSA Mandibular Advancement Devices Optimized by Jaw Movement Monitoring
A late-breaking abstract from SLEEP 2024 shows the effect of mandibular devices on respiratory effort, and its overall impact on OSA.
Novel Mouthguard Device Significantly Reduces Nightly Sleep Apnea Events
An alternative device to CPAP shows clinical benefit and long-term patient adherence in new SLEEP 2024 trial data.
Persistent Insomnia Symptoms Linked to a Greater Depression Risk
A study presented at SLEEP 2024 found persistent or progressive insomnia symptoms are linked to a greater depression risk than subthreshold cases with gradual improvement.
Seltorexant Meets Primary, Secondary Endpoints in Phase 3 Trial for MDD, Insomnia
Announced on May 29, 2024, data from the MDD3001 trial indicate use of seltorexant was associated with meaningful improvements in depressive symptoms and sleep disturbances.
Why Are Adult ADHD Cases Climbing?
Julie Thomas, MS, DMSc, PA-C, discusses why ADHD cases may go undetected into adulthood, and the methods to treat such patients.
Zodasiran Reduces Triglycerides, ANGPTL3 in Mixed Hyperlipidemia in ARCHES-2 Trial
A phase 2 trial suggests zodasiran significantly reduces triglycerides in patients with mixed hyperlipidemia, showing dose-dependent improvements in lipid profiles.
How Psoriatic Arthritis Presentation, Treatment Has Evolved
Benjamin J. Smith, DMSc, PA-C, discusses the importance of defining comorbidities in diagnosing PsA, as well as prescribing biologics.
Alan Bonder, MD: Phase 2 Data for Combination Obeticholic Acid, Bezafibrate in PBC
Bonder explains key therapeutic targets in primary biliary cholangitis and why combination obeticholic acid and bezafibrate may be a promising option.
Optimizing Diabetes Therapies with New Classifications
Ji Hyun “CJ” Chun, MPAS, PA-C, BC-ADM, explains how the adoption of 5 new diabetes subtypes may foster precision care.
Anthony Lembo, MD: Exploring Probiotics for IBS Treatment
Lembo describes the potential of a multi-species synbiotic for the treatment of IBS based on findings from an exploratory study he presented at DDW.
Iptacopan Reduces Proteinuria, Demonstrates Benefit in C3 Glomerulopathy
In the APPEAR-C3G trial, iptacopan reduced proteinuria by 35.1% in patients with C3 glomerulopathy, with Novartis planning regulatory submissions for C3G before the end of 2024.
Vlado Perkovic, MBBS, PhD: Semaglutide's Role in CKD Based on FLOW Results
Vlado Perkovic, MBBS, PhD, discusses the results of the FLOW trial and their implications for clinical practice at ERA 24.
Brian Lacy, MD, PhD: Assessing, Treating Chronic Abdominal Bloating and Distension
Lacy reviews key considerations for the diagnostic evaluation and treatment of abdominal bloating and distension based on his session at DDW.
Elizabeth Aby, MD: Financial Burden in Adults Undergoing Liver Transplant Evaluation
Aby describes findings from a pair of studies presented at DDW exploring the prevalence and impact of financial burden in liver transplant candidates.
Prashant Singh, MD: Rethinking the Low FODMAP Diet for IBS-D
Singh explains a potential new approach to the low FODMAP diet based on findings from research he presented at DDW suggesting a simplified step-up method.
Intestinal Ultrasound’s Value for Assessing Disease Activity in IBD, with Noa Krugliak Cleveland, MD
Krugliak Cleveland explains findings from research she presented at DDW comparing intestinal ultrasound and conventional approaches to disease monitoring in IBD.
Oral JAK Inhibitors, Steroids Do Not Significantly Differ in Alopecia Hair Regrowth
A systematic review presented at AAPA 2024 showed insignificant differences in treatment outcomes between oral JAK inhibitors and oral steroids based on alopecia outcomes like SALT.
Caroline Sisson, MMS, PA-C: Updates in Pulmonary Function Testing
Sisson discusses the adoption of 2021 ATS / ERS guidelines, as well as the need for complementary testing and imagine to contextualize the full pulmonary patient.
Ali Rezaie, MD: Exploring a Palatable Approach to the Elemental Diet
Rezaie reviews findings from a prospective clinical trial of a novel palatable elemental diet, highlighting its 100% compliance rate and strong efficacy.
Should We Reclassify Diabetes Subtypes?
Ji Hyun “CJ” Chun, MPAS, PA-C, BC-ADM, explains the potential value of defining diabetes subtypes based on insulin, obesity and age factors.
Remo Panaccione, MD: GALAXI 2, GALAXI 3 Data for Guselkumab in Crohn’s Disease
Panaccione explains findings from GALAXI 2 and GALAXI 3 demonstrating guselkumab’s superiority to ustekinumab in Crohn’s disease, presented at DDW.
Addressing Non-Adherence in Resistant Hypertension, with Swapnil Hiremath, MD, MPH
Swapnil Hiremath, MD, MPH, discusses resistant hypertension, including using an evidence-based approach to management and addressing non-adherence.
Francisca Joly, MD, PhD: Apraglutide in Short Bowel Syndrome with Intestinal Failure
Joly explains the burden of parenteral support and the significance of new STARS data showcasing apraglutide’s potential in SBS-IF.
Primary Care Roles in Alzheimer Diagnosis, with Theresa Sivers-Teixeira, MSPA, PA-C
Sivers-Teixeira explains that while the care team should quickly expand once dementia has presented in screening, the primary care role stays consistent.
Heart Failure Treatment Outcomes and Contraindications
Ashley Malliett, DMSc, MPAS, PA-C, discusses the importance of timely diagnosis and initiated care, as well as contraindications for transplants and LVAD.
Novel Endoscopy System Feasible for Evaluation of Upper GI Diseases
A cable-transmission magnetically controlled capsule endoscopy showed comparability to conventional methods in upper GI tract examinations and lesion detection.
Getting Black Men Involved in Their Health Care, Clinical Research
Aaron Henry, PA-C, MSHS, discusses why preventive care opportunities are often missed in Black men, and how community-based interventions may help.
Patient Involvement in Advanced HF Treatment, with Ashley Malliett, DMSc, MPAS, PA-C
Malliett discusses the signs that a caregiver should refer to an HF specialist for advanced care options, including LVAD and heart transplant.
Naim Alkhouri, MD: Interim Analysis of Phase 2 Survodutide Data Show Promise for MASH, Fibrosis
Alkhouri explains survodutide’s mechanism of action as a glucagon/GLP-1 receptor dual agonist and reviews key findings about its use in MASH from the interim analysis.
Blood-Based Test Offers Effective Screening Option for Colorectal Cancer
Data from PREEMPT CRC reveal the blood-based screening test demonstrated a 79.2% sensitivity for detecting colorectal cancer.