The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
ESA Hyporesponders More Likely to Receive Higher Doses of Daprodustat, ESA
At the end of the study period, the median dose of daprodustat and ESA were higher among the ESA-HR cohort when compared with the non-ESA-HR group.
Clinical Quiz: AGA Recommendations on Endoscopic Eradication Therapy of Barrett’s Esophagus
A detailed overview and accompanying quiz on the recommendations made by the AGA in their 2024 guideline on endoscopic eradication
REGENERATE: Final Results for Obeticholic Acid for Pre-Cirrhotic Fibrosis Due to NASH
End-of-study results from the phase 3 REGENERATE study were presented at DDW and highlight obeticholic acid’s trend in benefit for clinical outcomes.
GALAXI 2 & 3: Guselkumab Superior to Ustekinumab for Crohn's Disease
Both doses of guselkumab exhibited statistical superiority on all prespecified pooled endoscopic endpoints versus ustekinumab in Crohn's disease.
STARS: Apraglutide Reduces Parenteral Support in Patients with Stoma, Colon-In-Continuity
New STARS data were presented in a late-breaking abstract at DDW and build upon positive topline results for clinical responder rates and reductions in parenteral support.
Paul Feuerstadt, MD: Safety, Efficacy of Live-jslm in Patients Taking Concomitant Medications
Feuerstadt breaks down findings from an ad hoc analysis of PUNCH CD3 and what the results suggest about the use of live-jslm (Rebyota) in patients taking concomitant medications.
Depressive Symptoms Linked to Higher Risk of Peripheral Arterial Disease
During follow-up, rates of incident PAD were higher among patients with depressive symptoms compared with those without depression.
Aaron Henry, PA-C, MSHS: Regaining Black Male Patient Trust in the Doctor's Office
Black men face significantly worse health outcomes in the US. Henry explains why the clinician needs to focus on building more authentic trust in their interactions.
Multitarget DNA Stool Testing Kits Could Reduce Colorectal Cancer Screening Non-Compliance
An assessment to improve colorectal screenings by shipping Cologuard kits to non-compliant patients proved beneficial for a Mayo Clinic research team.
Toby Maher, MD, PhD: Improving Lung Function with ENV-101 Treatment of Idiopathic Pulmonary Fibrosis
These late-breaking data on drug candidate ENV-101 were presented at ATS 2024 and resulted from a new study on the drug’s effect on individuals with IPF.
How to Adequately Screen for and Treat Cognitive Decline in Primary Care
James R. Kilgore, DMSc, PhD, PA-C, discusses a new primary care screening tool for cognitive decline, plus lifestyle interventions that may complement drugs.
Depression Screening: Challenges and Solutions at the Primary Care Level
Beth Browning, PA-C, LPC, provides advice for busy primary care providers to efficiently incorporate timely and treatment-initiating depression screening.
Guselkumab Achieves Clinical, Endoscopic Remission in Ulcerative Colitis
The phase 3 QUASAR Maintenance study met its primary endpoint of clinical remission and demonstrated statistically significant endoscopic remission rates in UC treatment.
The Impact of GLP-1RA Use in Patients with IBD, with Priya Sehgal, MD, MPH
Sehgal explains the safety and efficacy of GLP-1RAs in patients with IBD as well as the impact on inflammatory biomarkers.
Finerenone Treatment Slows Chronic Kidney Disease Progression After Heart Failure Hospitalization
A numerically slower decline in eGFR was reported in the finerenone cohort after hospitalization for heart failure when compared with placebo.
Oriana Damas, MD: Intervals of a Low-Calorie, Plant-Based Diet Show Promise for UC
Damas explains key findings from her pilot study exploring intervals of a low-calorie plant-based diet as adjunctive therapy to medication in patients with ulcerative colitis.
Ali Rezaie, MD: Trends in GLP-1RA Use Among Nondiabetic, Nonobese Patients
Rezaie describes recent trends in GLP-1RA prescription patterns from his population-based research presented at DDW, highlighting increases in off-label use.
Tailoring Chest Pain Diagnostics to Patients, with Kyle Fortman, PA-C, MBA
Fortman reviews the state of the 2021 AHA/ACC guideline recommendations to pursue shared decision making and cost-efficient testing strategies.
Michael Dolinger, MD: Recognizing Intestinal Ultrasound’s Potential in Ulcerative Colitis
Dolinger reviews findings from his research presented at DDW about the use of intestinal ultrasound response for predicting endoscopic outcomes in children with UC.
James R. Kilgore, DMSc, PhD, PA-C: Cognitive Decline Diagnostics
Kilgore reviews early cognitive decline tools include AD8 and MoCA, and how they should be utilized at the primary care level.
Sweat-Based Wearable Device Monitors Key Markers of IBD Activity
TNF-α levels in the sweat correlate with serum values in patients with IBD, suggesting the wearable's feasibility in non-invasive disease monitoring.
Solutions to Prevent Climate Change-Related Illness, with Janelle Bludorn, PA-C
Bludorn reviews preventive measures and strategic collaboration to ensure high-risk patients for conditions like heat stroke are identified before an acute event occurs.
Kyle Fortman, PA-C, MBA: Troponin and Heart Injury Risk Screening Recommendations
An AAPA 2024 session reflected on the joint AHA/ACC chest pain guidelines, particularly the adoption of high-density troponin level testing since 2021.
Exploring Diet’s Role in Managing Ulcerative Colitis, with Oriana Damas, MD
Damas explains what inspired her research about the impact of a low-calorie plant-based diet on clinical response to medication in patients with ulcerative colitis.
What Should the American Academy of Physician Associates Focus on in 2025?
During AAPA 2024, a group of session presenters provide recommendations for the next year's agenda based on trends and development.
Microbiota-Focused Dietary Modulation May Improve MAFLD Management
Microbiota differences between individuals with and without MAFLD were associated with dietary intake and clinical outcomes.
GLP-1 Agonist Safety Risks and Obesity Stigma with Kevin Peterson, MD, MPH
Peterson reviews the gastric and hormonal events linked to drugs like tirzepatide, before considering whether incretin therapies will help to finally embrace obesity as the medical condition it is.
Breath Analysis Can Aid Clinical Characterization of Microbiome Metabolism
Findings were presented at DDW and highlight the feasibility of breath analysis for microbiome metabolic characterization in the digestive system.
Wei Zhang, MD, PhD: Recognizing Disparities in Hepatocellular Carcinoma Diagnosis, Care
Zhang explains disparities in HCC care and the negative impact on long-term outcomes, also addressing potential considerations for vulnerable patient populations.
Study Assesses Predictive Markers of Resmetirom Histological Response in MAESTRO-NASH
Results presented at DDW detail the association between ALT, Fibroscan CAP, Fibroscan VCTE, and histological response to resmetirom in patients enrolled in MAESTRO-NASH.