Latest Conference Articles

A review of six Phase 3 studies shows that tofacitinib is more effective for rheumatoid arthritis treatment than regimens including placebo and a disease modifying anti-rheumatic drug or methotrexate as monotherapy or in combination therapy.

In a phase 3 study, ixekizumab showed significant, clinically meaningful improvements of disease activity and physical function for patients with psoriatic arthritis.

Highly trained female athletes showed no sign of a negative effect on their hearts after intense workouts--contradicting studies that found such maximal excercise can be counter-productive, researchers said at the AHA meeting in Orlando, FL.

Heart disease presents differently in women, and a drug for angina that works for most men did not help most women with their angina, researchers reported today.

Injecting globs of a biopolymer based on brown algae into the heart muscle of patients with advanced heart disease helped halt or reverse disease. The procedure is meant to thicken the ventricle wall. That reduces pumping stress.

An investigational drug called andexanet alfa that can reverse the anticoagulant effects of FXa inhibitors met all primary and secondary efficacy endpoints, researchers said in a late-breaking clinical trial report at the AHA meeting in Orlando.

In patients with active rheumatoid arthritis symtoms that persisted even though they were taking methotrexate, baricitinib (Lilly/Incyte) treatment led to "significant improvements" researchers reported at the American College of Rheumatology Annual Meeting in San Francisco, CA.

Patients with rheumatoid arthritis who received sarilumab plus a DMARD who did not respond to anti-TNF medications showed statistically significant and clinically meaningful changes from baseline in fatigue, morning stiffness, pain, productivity, and participation at week 24.

Results from the MEASURE 1 trial suggest that about 80% of patients with ankylosing spondylitis had no radiographic progression in the spine on x-ray assessment after a 2-year course of secukinumab.

Analysis of data from the PEGASUS-TIMI 54 trial showed high rates of treatment discontinuation due to adverse events such as bleeding and dyspnea, with the highest rate occurring in the first year of treatment. Patients who stuck with treatment experienced a reduction in cardiovascular death, myocardial infarction, and stroke.

Patients with persistently active systemic lupus erythematosus (SLE) benefit from repository corticotropin injection (RCI).

Chest pain is one of the most common reasons that patients visit the emergency room, and the use of troponin testing can help cut down the time between first medical contact to final patient disposition.

Intravenous administration of tissue plasminogen activator (tPA) appears safe in selected patients who were already on novel oral anticoagulants (NOACs) a team reported at the American Heart Association Annual Scientitific Session in Orlando, FL.

Blocking IL-23p19 with an investigational Boehringer-Ingelheim compound called BI 655066 got better results than ustekinumab (Stelara/Janssen) in patients with moderate to severe plaque psoriasis

Other than joint replacement, not much works in treating osteoarthritis of the knee. A Brazilian research team said it has had success with intra-articular injections of ozone.

Compared with placebo, treatment with odanacatib consistently reduced fracture risk across a range of subgroups in a phase 3 clinical trial.

In phase 2 data, ABT-494 showed a significant dose response over placebo in treating rheumatoid arthritis.

Registering with multiple organ transplant centers may give wealthier patients an edge over less affluent patients who may be more deserving of a transplant.

A biologic agent called SB5 worked as well adalimumab,researchers reported at the American College of Rheumatology meeting in San Francisco, CA.

Depending on where people live their ability to do a simple exercise like walking can be greatly affected. How they choose to incorporate walking into their lives can go a long way in determining their overall health.

Students around the world are taught the benefits of healthy eating but sometimes that message does not always reach its desired audience effectively. Because of that new efforts are underway to better get the message across.

The Fat Fibre Sodium Score was created using the top three most predictable cardiovascular risk-reducing food categories and offers a quick, easy way to evaluate nutrition changes during post-cardiac rehabilitation.

The significant others of patients undergoing implantable cardiac defibrillators (ICDs) have long been concerned about continuing sexual activity following the implantation.

Heart disease is the number one killer of US women, but a national survey found cardiovascular health is not on most women's radar.

For overweight adults with type 2 diabetes, study results show that even light walking was linked to an average 10-point drop in blood pressure.

There are many anti-thrombotics available. An industry study showed apixaban had the best record of dissolving clots without causing major bleedign.

A recent study assessed whether a mobile app for the Android can promote better eating and exercise habits which can lead to improved heart health.

Tissue plasminogen activator (tPA) can dissolve lethal clots in the lungs but also carries a risk of excessive bleeding. Tennessee researchers reported on a new approach that worked better in a mouse study.

Type 2 diabetes drug empagliflozin significantly diminished the incidences of hospitalizations and even death from heart failure.

Previous studies have shown that less than one-third of patients discharged from the hospital for acute coronary syndrome actually remain abstinent from smoking.