The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Hydroxychloroquine Reduces Risk of Cardiovascular Events in Rheumatoid Arthritis
November 18th 2014The anti-arthritis drug hydroxychloroquine dramatically reduces the risk of cardiovascular morbidity and mortality in the disease, according to research presented here at the 2014 meeting of the American College of Rheumatology.
Mom's Pre-pregnancy Weight Impacts Risk of Dying Decades Later
Adults whose mothers were overweight prior to pregnancy have a higher risk of dying from cardiovascular disease, according to new research presented at the American Heart Association (AHA) Scientific Sessions 2014.
UK Mystery: Why More Endocarditis?
The United Kingdom has a medical mystery on its hands: what is causing a recent increase in infective endocarditis? One theory is that the uptick is due to a change in dental care. The UK's National Institute for Health and Care Excellence amended the rules on dental procedures, so patients no longer routinely get prophylactic antibiotics before invasive oral procedures.
Hypertrophic Cardiomyopathy Drug Treatment Disappoints
The most common cause of sudden cardiac death in young people is hypertrophic cardiomyopathy, an inherited condition that can lead to heart failure, angina, arrhythmia and sudden cardiac death. There is no medical treatment shown to halt or reverse the progression of the disease-just palliative care or surgery.
Losartan Trial for Marfan Syndrome Has Negative Results
Cardiologists treating pediatric patients with Marfan syndrome were hopeful that positive results from animal studies using losartan would be replicated in humans. But in a comparison of losartan with atenolol, researchers found no difference in the drugs' performance.
ODYSSEY Alternative Trials Show Promise for Hypercholesterolemia Patients
For patients with a statin intolerance, getting the treatment they need to manage their cholesterol levels can be difficult. A recent study has shown that a new class of drugs known as PCSK9 inhibitors could help effectively manage cholesterol levels in this patient population.
Fighting the Hollywood Heart Attack
In the Hollywood version of the heart attack, patients clutch their chests, gasp for air, and often keel over. Real life isn't usually like that. But the problem for cardiologists and other physicians whose patients have cardiac events, is that the patient may not realize he or she has had one.
Dual Antiplatelet Therapy: 6 Months as Good as 12?
During a question-and-answer session at the American Heart Association (AHA) Scientific Sessions 2014, Stefania Schüpke, MD discussed the results of her ISAR-SAFE study of the dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation is still unknown.
Pulse Oximetry Law Finds Newborns' Heart Problems
Undetected neonatal heart defects can cause a variety of serious problems, including an increased risk of death. A recently enacted New Jersey law mandating screening for congenital heart defects has uncovered cases of congenital heart problems and likely saved lives.
LCZ696 Changing the Course of Heart Failure One Patient at a Time
Heart failure is highly debilitating and life threatening – nearly half the patients who die from cardiovascular causes do so suddenly when their heart simply stops pumping, well before medical intervention is even possible.
More Intensive Blood Pressure Goals Reserved for Most Severe Kidney Disease: KDIGO
November 17th 2014Recent updates by the 8th Joint National Committee (JNC 8), the American and International Societies of Hypertension (ASH-ISH), and KDIGO recommend target blood pressure of less than 140/90 mm Hg for most individuals, including those with CKD.
LCZ696 Could Set New 'Gold Standard' for Heart Failure Treatment
With heart failure increasing in prevalence as the US population ages, early detection and more effective treatments are important. Now, data from clinical studies show that treatment with the experimental angiotensin receptor neprilysin inhibitor LCZ696 can significantly reduce patients' risk of sudden death and hospitalization.
Updated Blood Pressure Guidelines from Major Bodies Agree on Targets in Kidney Disease
November 17th 2014Two major sets of hypertension guidelines released in 2014 contain more common threads than differences, and are intended to serve different purposes. Clinicians seeking guidance for managing hypertension in chronic kidney disease (CKD) can look for this common ground to avoid "guideline overload."
Increased Risk of Ischemic Events Upon Discontinuation of Prasugrel
Kirk Garratt, MD, presenting at the 2014 American Heart Association Scientific Sessions, said "The TAXUS Liberte Post-approval Study (TL-PAS) was designed to provide long-term safety and efficacy information about the clinical outcomes for the TL stent combined with the use of prasugrel and aspirin."
VP Cheney's Other Role: Heart Patient
Former VP Dick Cheney spoke at AHA 2014 about his experiences as a model heart patient. Speaking with his cardiologist, Jonathan Reiner, MD, of George Washington University, Cheney recounted his 5 heart attacks, a CABG procedure, defibrillator implantation, getting a left-ventricular assistive device, and at age 71, a heart from an anonymous donor.
Hypertension Guidelines Still Leave Room for Clinical Judgment
November 17th 2014Guidelines for hypertension have converged on a blood pressure target of less than 140/90 mm Hg for most individuals with chronic kidney disease (CKD). However, studies still need to clarify optimal BPs for advanced disease and optimal cardiovascular prevention.
Left Heart Remodeling in Patients with Transcatheter Aortic Valve Replacement
"Left heart remodeling after transcatheter aortic valve replacement (TAVR) is poorly characterized," according to Marco Magalhaes, MD, who presented at the American Heart Association (AHA) Scientific Sessions 2014.
Stressing the Importance of Physical Activity to Patients of All Ages
The days of children playing outside from sunrise to sunset are long gone, and many children also do not get enough exercise at school during gym or recess. Knowing this, it is important for physicians to educated parents and children on the beneficial effect physical exercise can have on children's health now and later in life.
Do Men and Women Really Handle Stress Differently?
Living in the 21st century is stressful for just about everyone. What can change the way it affects a person's life is how they handle it. A recent study looked at whether women handle stress differently and what it can mean to a person's overall health.
High-caffeine energy drinks can cause serious cardiac and neurological symptoms in children. At the 2014 American Heart Association Scientific Sessions in Chicago, IL, Steven Lipshultz, MD, called for new labeling on the drinks that would spell out risks, particularly for the adolescent consumers manufacturers target for marketing.
Are Hospitals a Bad Place to Have a Heart Attack?
Could hospitals be a bad place to have heart attacks? That's the finding of a North Carolina research team that looked at data from 303 California hospitals. Patients who had heart attacks while hospitalized for a non-cardiac ailment had a more than 3-fold greater in-hospital mortality than patients taken to a hospital.
Clot-prevention Therapies: No Clear Answer
Dual antiplatelet blood-thinning therapy (DAPT) immediately after stenting with a drug-eluting device has been shown to prevent major cardiac events and stent thrombosis in most patients. Current American College of Cardiology and American Heart Association guidelines recommend 12 months of therapy post-stenting. But out of concern over potential risks of continuing the drugs longer, or even indefinitely, the US Food and Drug Administration (FDA) asked device manufacturers to study the longer-term consequences of the therapy.
Making Improvements in Treating Kidney Disease
In the past there were few effective treatment options for serious conditions such as hepatitis C and lupus. However, recent scientific advances offer physicians and patients greatly improved options for effective management of these conditions, with fewer adverse events.
Pharmacogenetics Helps Fine-Tune Warfarin Dosing in Kidney Disease
November 16th 2014Though warfarin has long been the mainstay of anticoagulation in atrial fibrillation (AF), dosing is complicated by a host of factors, and the drug has a famously narrow therapeutic range. One way to fine-tune warfarin therapy is to account for genetic variation.
Consider Individual Risks, Benefits for Anticoagulation in Chronic Kidney Disease
November 15th 2014Anticoagulation is recommended for members of the general population with atrial fibrillation, but its significant risks must be weighed carefully in the medically fragile chronic kidney disease population.