The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Jonathan Stine, MD: Exercise’s Benefit in MASH is Independent of Weight Loss
Stine reviews findings from a posthoc analysis of the NASHFit trial suggesting the impact of exercise on MASH resolution, even without weight loss.
Intensive Blood Pressure Regimen Lowers CVD Risk in People with T2D
Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with diabetes in the BPROAD trial.
SUMMIT Trial Proves Tirzepatide's Benefit in HFpEF with Obesity
Tirzepatide reduced the risk of heart failure hospitalization or cardiovascular death by 38% and improved body weight by up to 21% in the SUMMIT trial.
Telehealth Could Address HCV Care Barriers, Expand Treatment for People Who Inject Drugs
Zoi Papalamprakopoulou, MD, explains telehealth’s potential to aid HCV treatment in high-risk populations and how patients perceive this care modality.
John Stone, MD, MPH: Inebilizumab Efficacious for IgG4-Related Disease in MITIGATE Study
Stone discussed findings from the first randomized, double-blind, placebo-controlled trial for IgG4-related disease.
Glucocorticosteroid Use for Rheumatoid Arthritis Increases CVD, Infection Mortality Risk Even After Cessation
People who used GC for over 2 years and 3 years had elevated risks of CVD and infection-related mortality, respectively, that never returned to pre-GC use levels.
Study Highlights Real-World Characteristics of Providers Treating Psoriasis in US
In this cross-sectional survey analysis, new insights were explored regarding clinical practice patterns and treatment outcomes within dermatology practices in the US.
Wei Zhang, MD, PhD: Optimizing Post-Liver Transplant Care for High-Risk Patients
Zhang describes how a novel multidisciplinary care clinic has helped reduce relapse after transplant in patients with alcohol-associated liver disease.
Idorsia Launches Aprocitentan (TRYVIO) in US For Treatment of Hypertension
Once-daily aprocitentan is indicated to help lower blood pressure in adult patients with hypertension who are inadequately controlled on other medications.
IL-18 Levels Associated With Long COVID Risk in People With Rheumatic Diseases
IL-18 levels were consistently lower across participants with different SARDs, remission status, and COVID-19 disease characteristics.
VTP-300, Nivolumab Combination Shows Promise for Functional HBV Cure in Phase 2b Trial
New phase 2b data suggest a combination of VTP-300 and low-dose nivolumab can stimulate immune response and induce HBV functional cure.
Seladelpar (Livdelzi) Demonstrates Long-Term Benefit for Primary Biliary Cholangitis
Findings from a 2.5-year interim analysis from the ongoing phase 3 ASSURE study highlight seladelpar’s sustained efficacy and long-term safety for PBC.
New Review Highlights Variability in Clinical Features, Comorbidities of Biliary Atresia
A study presented at NASPGHAN 2024 reveals rising incidence rates and improved survival outcomes of Biliary Atresia in the US.
Study Finds Benefits and Risks in Cannabis Use for Rheumatoid Arthritis
While an effective and promising strategy for chronic pain relief, more research on long-term cannabis usage is needed.
Kara Margolis, MD: Link Between Maternal SSRI Exposure, Increased Constipation Risk in Infants
Maternal SSRI use was linked to a higher risk of constipation in infants, while untreated maternal depression was tied to colic. Margolis discussed these findings at NASPGHAN.
Debra Silberg, MD, PhD, on Celiac Disease: “The Guidelines Are Really Helpful, but They Have to be in the Right Hands”
Silberg urges wider physician education on celiac screening, stressing that guidelines must reach primary care to address disparities and misconceptions.
Age, Race, Ethnicity Disparities Hinder Celiac Disease Screening, with Debra Silberg, MD, PhD
A study presented at NASPGHAN 2024 found only 10% of eligible kids were screened for celiac disease. Debra Silberg, MD, PhD, urges unbiased, consistent screening.
Study Finds Most Children with Hep C have Developmental Disorder, Learning Difficulty
Research presented at NASPGHAN 2024 found most children with chronic hepatitis C had neurodevelopmental disorders, highlighting the need for proactive care.
Trends in Risk & Management Strategies for Water Bead Injuries, with Patrick Reeves, MD
A Q&A with a pediatric gastroenterologist on new data detailing trends in water bead injuries in the US from 2013 through 2023.
NASPGHAN 2024: PEDFIC Data Highlight Safety of Odevixibat in Pediatric Patients with PFIC
PEDFIC data at NASPGHAN 2024 show mild, transient diarrhea events with odevixibat for cholestatic pruritus in PFIC, resolving in most cases.
Water Bead Injuries, Need for Escalating Care Becoming More Common in United States
A 10-year study reveals a surge in water bead injuries in young children, with an increase in cases requiring surgical intervention for bowel obstructions.
Lauren Collen, MD: Advanced Combination Therapy May Be Effective Option for Pediatric Refractory IBD
At NASPGHAN 2024, Collen told HCPLive the promising early data of advanced combination therapy for pediatric refractory IBD although hurdles exist.
Total Bilirubin, MMP-7, and TBA Show Promise for Predicting Liver Survival in Biliary Atresia
Meta-analysis of 30 studies highlights serum markers as prognostic tools for liver survival post-portoenterostomy in biliary atresia.
Lauren Collen, MD: Some Fragrances May be More Prevalent in Exposomes of Children with Crohn’s Disease
HCPLive spoke to Collen at NASPGHAN 2024 about early research on environmental exposures prevalent in children with Crohn’s Disease.
Linaclotide Effective for Functional Constipation in Children with Neurodevelopmental Disorders
Linaclotide trial shows effective constipation relief for pediatric patients with neurodevelopmental disorders, with high treatment adherence and safety profile.
Machine Perfusion Could Help Address Transplant Crisis for Pediatric Liver Diseases
New data from the UNOS database presented at NASPGHAN 2024 details characteristics and outcomes of pediatric liver transplant patients receiving machine perfused organs.
Children Who Contracted COVID-19 Twice as Likely to Develop IBS, Study Finds
NASPGHAN 2024 data suggests children and adolescents with a history of COVID-19 were twice as likely to develop IBS during the follow-up period.
Impact of Long Hospital Stays on Pediatric Gastroparesis Management with Christian Sadaka, MD
At NASPGHAN 2024, Sadaka shared results of a study demonstrating the factors associated with a longer hospital stay for children with gastroparesis.
EoE KIDS Suggests Dupilumab Offers Benefit Regardless of Prior Therapy Exposure
Post-hoc analysis of EoE KIDS trial shows dupilumab benefits for pediatric eosinophilic esophagitis, effective in patients with prior therapy limitations.
Christian Sadaka, MD: Significant Increase in Pediatric Gastroparesis Hospital Admissions After COVID-19
HCPLive spoke to Sadaka at NASPHAN 2024 about the increase in hospital admissions among children with gastroparesis after the COVID-19 pandemic.