The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Arterial Stiffness Bidirectionally Associated with General, Central Adiposity in Adolescents
Data show cfPWV at 17.7 years was independently and directly associated with total fat mass and trunk fat mass at 24.5 years.
Adipocytokines, Oxidized LDL Aid in Metabolic Balance in Hypertensive Patients.
Investigators added that they interact directly with the insulin signal transmission pathways.
Complete Revascularization in ACS Patients Related to Cardiorespiratory Fitness
Investigators also reported that cardiorespiratory fitness was superior in patients with complete revascularization when compared to the patients with incomplete revascularization.
Triple Therapy In T2D Care Linked To Lower Rate Of Hepatic Steatosis, Fibrosis
Patients with type 2 diabetes treated with triple therapy had less hepatic steatosis and fibrosis and significantly improved insulin sensitivity versus conventional therapy.
Investigators Confirm Efficacy of Dasiglucagon for Treatment of Hypoglycemia
The team estimated the time to individual plasma glucose recovery following exposure to the medication.
Hyperinsulinemia Rates in US Adults Significantly Increased Over 20 Year Period
Data show the age-adjusted prevalence of hyperinsulinemia in adults without diabetes increased by 18% in the study population between 1999 - 2000 and 2017 - 2018.
Severe COVID-19 Symptoms Recorded in Patients with Nonalcoholic Fatty Liver Disease
In keeping with earlier data, investigators suggested that metabolic syndrome was associated with severe cases of infection.
José-Alain Sahel, MD: Safety, Efficacy of Optogenetic Treatment for Retinitis Pigmentosa
At AAO 2021, Dr. Sahel discussed the findings of the PIONEER trial on the combination of an optogenetics device and gene therapy in treatment of RP.
Robert L. Avery, MD Highlights Results on RGX-314 For the Treatment Of Wet AMD
Dr. Avery discusses the positive results of RGX-314 gene therapy, noting dramatic reduction in need for therapy, with stable vision and good thickness results
Dilsher S. Dhoot, MD: Efficacy of Brolucizumab in Treatment of Diabetic Macular Edema
Dr. Dhoot discusses data on visual acuity from the phase 3 KESTREL and KITE trials, comparing brolucizumab to aflibercept at 52 weeks.
Abrocitinib Dosing Effective in Atopic Dermatitis Management
Investigators said that patient-reported outcomes from the 2 abrocitinib groups showed greater efficacy than the dupilumab and placebo groups.
Study Evaluates Sun Protection Awareness in Adolescents
Respondents suggested that increasing product availability and demonstrating the consequences of sunburn could increase sun protection among young people.
Arshad Khanani, MD Discusses Adverse Ocular Events After Brolucizumab Treatment
Dr. Khanani highlights data from MERLIN showing noninferiority of brolucizumab to aflibercept in nAMD treatment, but a higher rate of intraocular inflammation.
Veeral Sheth, MD: Identifying Durability, Safety of GB-102 in Wet AMD Treatment
Dr. Sheth discusses the data from the late-breaking Phase 2B ALTISSIMO study.
Boni Elewski, MD: Biologics for Pediatric Psoriasis Patients
Dr. Elewski hopes that in the future more clinicians will prescribe biologics such as secukinumab and etancercept for the treatment of psoriasis.
Lisa Swanson, MD: Detailing Infantile Hemangioma
Though not all hemangioma last past 10 years old in pediatric patients, some untreated hemangioma are associated with high risk of ulceration.
Saakshi Khattri,MD: Evolving Therapies for Psoriatic Disease
Though Dr. Khattri felt the diagnosis of psoriatic arthritis had been “stagnant”, the inclusion of biologic therapies and more has been a welcomed change.
Boni Elewski, MD: Safety and Efficacy of New Psoriasis Therapies
Certain biologics such as infliximab have aided psoriasis patients in the mitigation of symptoms from the COVID-19 virus.
Lisa Swanson, MD: The Psychology of Pediatric Chronic Skin Conditions
Dr. Swanson also details the effects of the COVID-19 pandemic on her practice with the implementation of telemedicine.
Seemal Desai, MD: The Promise of JAK Inhibitors in Vitiligo Management
Dr. Desai says that Janus kinase inhibitors present a new mechanism of action, with effects on cytokine signals that signal inflammation in atopic diseases.
Boni Elewski, MD: The Future of Psoriasis Therapy
Dr. Elewski speaks of the safety and efficacy of several new and developing therapies, including bimekizumab treatment which has yet to be approved in the United States.
Lisa Swanson, MD: Detailing Therapies for Pediatric Skin Conditions
Swanson noted the efficacy and safety of dupilumab, which she feels revolutionized patient care.
Saakshi Khattri, MD: Diagnosing Psoriatic Arthritis Early in Psoriasis Patients
Dr. Khattri speaks of the benefits of diagnosing the condition early in psoriasis patients, as well as what dermatologists can do before referring a patient to a rheumatologist.
Seemal Desai, MD: Advancements in Vitiligo Therapies
New therapies are breaking ground in the world of vitiligo research, which Dr. Desai believes will result in FDA approvals in the coming years.
Carl D. Regillo, MD: Key Factors of Faricimab In Neovascular AMD Treatment
Dr. Regillo discusses the efficacy and durability of faricimab for wet AMD treatment in TENAYA and LUCERNE, showing noninferiority to aflibercept.
Rishi P. SIngh, MD: Advances and Challenges in Neovascular AMD Treatment
Dr. Singh discusses the aging population in ophthalmology care, advances including port delivery systems, and the potential rapid uptake of faricimab in treatment.
US Patient Access to Ophthalmology Clinical Trial Sites Differs by Regions
A geographical study shows patients in areas with lower income, education, and higher rates of ophthalmic disease may be a greater distance from a trial site.
Rishi P. SIngh, MD: Durability of Faricimab in Neovascular AMD Treatment
Dr. Singh discusses results from TENAYA and LUCERNE on faricimab compared to afilbercept in patients with nAMD.
Ranibizumab Biosimilar FYB201 Provides Similar Efficacy, Safety in Phase 3 Trial
The COLUMBUS-AMD trial suggests the investigative biosimilar could benefit patients newly diagnosed with nAMD.
New Model Could Predict Cost of PDR Prevention with Aflibercept
A cost-based assessment of Protocol W and PANORAMA clinical data suggests diabetic retinopathy may be less costly to prevent than macular edema.