On the HCPLive news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.
Allergen Immunotherapy May Prevent Progression of Allergic Rhinitis to Asthma
Allergen immunotherapy can reduce symptoms of allergic rhinitis and asthma and decrease the need for medication, but it poses the risk of asthma exacerbation or anaphylaxis, particularly in patients with uncontrolled asthma.
Smoking Impairs the Effectiveness of Inhaled Corticosteroids
After 6 months of treatment with inhaled budesonide, 800 μg daily, bronchial hyperresponsiveness was greater and the proportion of eosinophils in induced sputum and improvement in lung function were lower in smokers than in nonsmokers with asthma.
There has been plenty of research to show that rehabilitation can help with the cognitive function of patients with multiple sclerosis. A recent study looked at whether advanced imaging can determine whether some patients will respond better to the therapy than others.
Brenda Banwell from Children's Hospital of Philadelphia: Diagnosing Pediatric Neuromyelitis Optica
In adult patients neuromyelitis optica is considered a rare enough condition. It is even more rare in children making the diagnosis and treatment a longer and more careful process.
MS: Laquinimod Trial Methods Questioned
The likelihood that a participant in a randomized, controlled trial receives laquinimod or placebo to treat relapsing-remitting multiple sclerosis (RRMS) could explain the differences in study results, according to recent research.
HIV: Software Finds 25% Patients in Washington, DC Not Achieving Viral Suppression
Nearly a quarter of HIV positive patients getting care through the Ryan White federally funded treatment program have not gotten their viral loads down. The analysis was made by the district's health department, which has used the data to address the problem.
Ludwig Kappos: New Studies Help Momentum Move Forward in Multiple Sclerosis Care
There are now more than a dozen medications approved for the treatment of relapsing multiple sclerosis, a treatment pending approval for primary progressive, and very early signs of hope for secondary progressive. As a result there was plenty of optimism at ECTRIMS as it left London and prepared for Paris next year.
Once-Daily Tiotropium Found to be Safe and Tolerable in Combination with Inhaled Corticosteroids
The percentage of patients with adverse events was comparable in the tiotropium and the placebo treatment groups in pooled data from seven phase 2 and 3 studies in nearly 3,500 adults.
Imaging Study Finds Systolic Dysfunction, but no Diastolic Dysfunction, in Children with Asthma
Contrary to the previously published literature on cardiac function in asthma patients, Turkish researchers observed no diastolic dysfunction in a group of 50 asthmatic children evaluated in a recent echocardiographic study, even with tissue Doppler imaging.
Weight Gain Worsens Asthma Control, According to Study
Investigators found poor asthma control in obese or overweight patients despite optimal treatment and significantly higher BMI values in those with uncontrolled asthma than in those with partially or totally controlled asthma.
Pediatric Asthma Flares May be Marked by Boost in Key Clotting Factors
Endothelial activation and levels of C-reactive protein, plasminogen activator inhibitor type-1, and von Willebrand factor increased during asthma exacerbations in a study of 22 pediatric patients.
Progressive multifocal leukoencephalopathy, also known as PML is a problem which can affect a select number of patients with multiple sclerosis as well as other conditions which involve the immune system. What can be done to address the condition is still being determined by the medical community.
Acute Posterior Multifocal Placoid Pigment Epitheliopathy Developed in One Woman After Flu Vaccine
“To our knowledge, only one case of APMPPE following human influenza virus vaccine was reported, and this case reportedly demonstrated a benign clinical course.†The researchers encourage doctors to be aware, though this case was both benign and extremely rare.
Analysis: AF Treatment Should Go Beyond Stoke Prevention
A meta-analysis of 104 cohort studies involving more than 9.5 million patients concludes that atrial fibrillation is associated with elevated rates of cardiovascular disease, renal disease and early death. Its authors conclude the treatment of AF should expand its focus beyond stroke prevention.
Bad Air and Blood Sugar? Study Attempts to Link Pollution and Diabetes Risk
Higher levels of nitrogen dioxide were associated with higher levels of HOMA-IR, glucose, insulin, and leptin. The degree of association, however, varied among the different populations. Effect estimates for pre-diabetic individuals were large and highly statistically significant, while the associations were smaller and weaker in non-diabetic individuals and those who had already developed T2DM.