Endocrinology

Treatment-experienced patients with HIV who switched to a tenofovir alafenamide-based treatment regimen maintained excellent virologic suppression while exhibiting significant improvements in both bone and renal safety.

Patients who are morbidly obese need a revised dosing protocol when getting vancomycin.

The US Food and Drug Administration requested three manufacturers of duodenoscopes – Olympus America, Inc. Fujifilm Medical Systems, USA, Inc., and Hoya Corp – to perform real-world postmarket surveillance studies duodenoscopes used to perform endoscopic retrograde cholangiopancreatography procedures (ERCP).

The "obesity paradox" suggests that patients with excess weight are associated with better survival among individuals with cardiovascular disease -a mysterious and confounding phenomenon that has been demonstrated in many clinical studies.

Cardiac complications with diabetes and the effects of bariatric surgery on diabetes control are discussed in the following slides.

The International Working Group on the Diabetic Foot (IWGDF) Guidance 2015 recently published its evidence-based international consensus guidance. This guideline addresses 5 specific areas of concern in diabetes.

Resistance to thyroid hormone (RTH) occurs in rare patients and its clinical presentation is considerably different than that seen in the usual hyperthyroid patient. Patients with this inherited condition produce inordinate levels of thyroid hormone because their negative feedback loop at the pituitary gland is metaphorically snipped. Concurrently, they have normal levels of thyroid-stimulating hormone.

Recurrent major depressive disorder episodes are linked to lower bone density in men, according to findings published in the Journal of Musculoskeletal and Neuronal Interactions.

An article published in Clinical Interventions in Aging outlined a large hospital's successful quality improvement interventions over 5 years to reduce medication errors in their large population of diabetic patients.

The FDA today approved two new diabetes drugs. The agency gave the nod to insulin degludec injection (Tresiba/Novo Nordisk) and insulin degludec/insulin aspart (Ryzodeg/Novo Nordisk)

Researchers looked at possible renal protective properties of an SGLT2 inhibitor.

Devoted soda drinkers began to lose their minds when an infographic outlining the harmful effects a single can of Coca-Cola has on the body in one hour began circulating the Internet. Now a new infographic has revealed what a Big Mac from McDonald's can do to the body in the same amount of time.

Our Sept. list of top news & research includes a report on increased diagnoses of thyroid cancer and disturbing stats on diabetes prevalence in the US.

In an effort to fight obesity and diabetes and promote healthier diet and lifestyle choices through targeted interventions, public health officials determined which regions of the US have the highest levels of soda and other sugar-sweetened beverage consumption.

Study involving parents of children with type 1 diabetes mellitus shows they need support and assistance in helping their children make healthy dietary choices.

Study results show that treating community-dwelling elders too zealously for elevated thyroid-stimulating hormone levels is a leading cause of thyrotoxicosis.

Diabetic kidney disease can take various forms and affect patients in different ways. How the disease progresses and what can be done to slow that progression is the focus of many researchers in the field.

Diabetes itself, not any specific glucose-lowering drug, is likely to blame for an increased risk of pancreatic disease, Danish researchers report.

Massive weight loss (MWL) provides obvious health benefits, including reducing morbidity and mortality risks, but it brings some medical and psychological challenges as well. MWL patients are often left with excessive amounts of sagging skin, particularly in the thighs, under the arms, around the abdomen, and around the face.

Precision medicine's role in the management of hypogonadism is still in its formative stages. Researchers suggest that identifying biomarkers associated with individual patients' treatment responses is possible.

Researchers from the University of Washington in Seattle reported that the use of avatars (digital representations of a coach, buddy, or teacher) improved user satisfaction in interactive, online weight management programs for obese teens.

Study results show patients who took statins following ischemic stroke were significantly less likely to have post-stroke early-onset seizures.

In 2010, about 3% of Americans had tried e-cigarettes. Today, around 10% of the population has tried them, with sales growing every year.

Middle-aged men with prediabetes are more likely than healthy peers to suffer from depressive symptoms and signs of andropausal syndrome.

New research into distal pancreatectomies indicates that women and overweight patients have an elevated risk of suffering endocrine function impairment that leads to glucose intolerance and diabetes mellitus.

Bariatric surgery has been shown to reduce the incidence of type 2 diabetes and albuminuria. However, data connecting the magnitude of weight loss and reduction in obesity-related comorbidities is limited.

A study published in Metabolic Syndrome and Related Disorders indicates that sodium glucose cotransporter-2 inhibitors (SGLT2 inhibitors, which affect both supply and demand pathways in the heart) may be the preferred treatment for diabetics with heart failure.

Fetal exposure to severe starvation or stress appears to elevate risk of hyperglycemia or type 2 diabetes (T2D) later in life. Similarly, low birth weight has been associated with glucose intolerance, suppressed insulin secretory capacity, and increased risk of T2D.

The connection between diabetes and gout is more complicated than thought. Individuals with type 2 diabetes are at increased risk of developing gout, but not because they have diabetes.