Endocrinology

Children with systemic lupus erythematosus (SLE)/mixed connective tissue disease (MCTD) often suffer from significant bouts of depression and potentially suicide ideation, a study in the Journal of Pediatrics determined.

A study in Postᶒpy adds to the growing evidence of a link between insulin and carbohydrate metabolism in the etiology and severity of acne vulgaris. While the clinical evidence on this connection is still disputed, the majority of recent studies has pointed to a significant connection between the condition and insulin levels.

There appears to be a positive correlation between higher antibiotic use and the development of type 2 diabetes, according to a study published in The Journal of Clinical Endocrinology & Metabolism.

New research on the link between diabetes and pancreatitis has shown a strong association between the severity of pancreatic dysfunction and subsequent risk of developing type 2 diabetes mellitus.

The US Food and Drug administration today issued a warning that the type 2 diabetes medicines sitagliptin (Januvia/Merck) linagliptin (Tradjenta/BI), and alogliptin (Nesina/Takeda) "may cause joint pain that can be severe and disabling."

A systematic review of alopecia areata (AA) in Clinical, Cosmetic & Investigational Dermatology highlighted the unpredictability and lack of treatment options for the condition. But it also pointed to a larger problem: more than half of patients with AA experience poor health-related quality of life (QOL). Patients with AA are at risk for depression and anxiety, atopy, vitiligo, thyroid disease, and other autoimmune conditions.

It is unclear how many people have pituitary incidentaloma, but imaging and autopsy studies indicate they are quite common and occur in up to one-third of patients. Fortunately, the vast majority of these serendipitously discovered tumors are clinically insignificant. A management guideline in the Annals of Endocrinology brings endocrinologists up to date on current thinking about pituitary incidentaloma management.

Most self-improvement intervention programs rely on self-monitoring, or increased awareness of bad habits, to help people change their behaviors. Traditionally, programs have used diaries, calendar notes, or check-ins at daily or weekly meetings to help individuals recognize and replace unhelpful routines. The October 2015 issue of Telemedicine and e-Health includes a study that describes how simple electronic feedback can help people with weight problems.

New research concludes that the association between celiac disease and exocrine pancreatic insufficiency (EPI) is strong enough that physicians should check for EPI when celiac patients suffer malnutrition or gastric distress despite adherence to prescribed diets.

Dr. Unger helps us kick off the Meet the Board series. Over the coming months the series will introduce you to the Endocrinology Network board.

Patients with the cystic fibrosis transmembrane conductance regulator gating mutation G551D have insufficient ion transport due to reduced channel-open probability. New information suggests that increased ion transport reduces disease burden in the pancreas, which prevents cystic fibrosis patients from digesting food properly and leads to exocrine pancreatic insufficiency in up to 90% of all cases.

Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease reported in the United States. Some researchers have hypothesized that TNF-α, as a mediator of inflammation, might be a therapeutic target for NAFLD since inflammation seems to be a component of its etiology.

A sleep apnea device may effectively slow the progression of diabetes in at risk patients.

A new trial of vitamin D replacement regimens in young people with cystic fibrosis and exocrine pancreatic insufficiency finds twice-weekly doses of vitamin D2 50,000 IU to be as effective as weekly doses of vitamin D3 50,000 IU.

With funding meant to bolster basic research and help make advances for a variety of conditions the fate of the 21st Century Cure Act is anything but secure even after passage by the US House of Representatives.

Study shows intramuscular injected bone marrow-derived mesenchymal stem cells may be able to restore the myelin sheath and nerve cells in diabetic sciatic nerves.

It may be cool to sip on a Coca-Cola that features your name right on the product, but a report that's been making the rounds details the metabolic roller coaster ride that drinking even a single can unleashes on the body.

At least 5 studies indicating that testosterone replacement therapy either has no effect on cardiovascular health -- or tends to improve it -- appeared during the 3-week period immediately after the US Food and Drug Administration's controversial decision to mandate warnings about the potential cardiovascular risks of such treatment.

Researchers have long known that single men tend to have more testosterone than comparable men in long-term relationships, but what about men in new relationships? A new study finds that testosterone generally remains at "single-man" levels until couples have been dating for more than a year.

Studies have shown that major depressive disorder (MDD) has a strong link to genetic factors, and many clinicians and researchers believe the same to be true for obesity.

A new investigation of the molecular and cellular mechanisms that produce diabetes may explain the strong association between cystic fibrosis and pancreatic complications.

With obesity on the rise, bringing with it an increased risk of diabetes, cardiovascular disease, and other conditions, food labels may soon get a facelift.

The US Food and Drug Administration on Friday approved the first cholesterol-lowering treatment in a new class of drugs known as proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors.

Columbia University's Informatics for Diabetes Education and Telemedicine (IDEATel) project, a 4-year Centers for Medicare and Medicaid Services-sponsored demonstration project, showed that a telemedicine intervention can improve glycemic, lipid, and blood pressure control.

Friday could be a big day for cardiologists. The FDA is due to rule July 24 on what could be the first available PCSK9 inhibitor, one of a new class of cholesterol-lowering agents meant to help patients who cannot get their LDL levels low enough with statins. New York City cardiologist David Vorchheimer, MD. talks about his hopes for the new drugs, and a few concerns

Both chronic pain conditions and obesity are major and increasing public health concerns, and the connections between the two have been firmly established in the medical literature. But as the prevalence of obesity worldwide continues to grow, a deeper understanding of this connection could potentially benefit both practitioners and patients.

When women present clinically with acne, hirsutism, and androgenetic alopecia, the likelihood is that the causative hormone is androgen. Collectively, these symptoms signal cutaneous hyperandrogenism.

New research into vitamin K deficiency among cystic fibrosis patients may help explain why exocrine pancreatic insufficiency increases the risk of pathological shortages.

A study evaluating glycemic response following insulin initiation for type 2 diabetes mellitus found that patients with higher depression parameters or distress at baseline had significantly higher rates of microvascular complications at baseline and higher HbA1c levels.

A woman's lung cancer risk is not impacted by her reproductive history or prior hormone use.