On the HCPLive Major Depressive Disorder condition center page, resources on the topics of medical news and expert insight into depression can be found. Content includes articles, interviews, videos, podcasts, and breaking news on MDD research, treatment, and drug development.
November 1st 2024
In a recent phase 2a trial, SPN-820, a novel intracellular moderator of mTORC1, decreased suicidal ideation by 80%.
October 23rd 2024
Updated Recommendations for Gestational Diabetes Streamline Screening Methods
June 16th 2014In response to the growing prevalence of gestational diabetes mellitus and its associated morbidities, much attention has been paid to the use of appropriate screening methodologies for the metabolic disorder.
Vortioxetine May Also Improve Cognition in Adult Patients with Major Depressive Disorder
May 6th 2014Study results presented at the 2014 APA annual meeting show patients treated with vortioxetine significant improvement in composite cognition scores compared to patients treated with placebo, independent of the drug's effect on their depression symptoms.
Growing Awareness for Ketamine Treatment in Depression and Anxiety
May 6th 2014When I first considered intravenous ketamine to treat severely treatment-resistant depression 4 years ago, I was in a scary, lonely place where I received a lot of skeptical questions and funny looks accompanying chirping crickets.
Desvenlafaxine Safe and Effective for Major Depressive Disorder in 'Real-world' Trial Setting
May 5th 2014Small, "naturalistic" study shows treatment with desvenlafaxine produces high rates of symptom improvement and remission with low rates of adverse events in patients with major depressive disorder.
Restoring the Path to Multidisciplinary Chronic Pain Management
Although the concept of delivering chronic pain care through multidisciplinary clinics is less than half a century old, John Loeser, MD, believes the model has already surpassed its peak in the United States, mainly due to financial reasons.
Predicting Positive and Negative Symptom Exaggeration in Chronic Pain Patients
Sometimes, chronic pain patients intentionally magnify or downplay their physical and mental symptoms during office visits. Despite that fact, little attention in the clinical setting is paid to underlying motives for positively or negatively biased self-reports.
Mindfulness-based Pain Care Provides Opioid Taper Support
Even if a chronic pain patient had been taking opioid medications exactly as prescribed, it would still be possible for the patient to experience negative cognitive and emotional responses to dose tapering that could amplify sensory pain and lead to opioid addiction.
Can a Smoking Cessation Drug Cause Neuropsychiatric Adverse Events?
March 7th 2014When encouraging and supporting patients to quit smoking, varenicline is unlikely to increase the risk of neuropsychiatric adverse events such as suicide, depression, and aggression, even in patients with pre-existing psychiatric illness.
Grouping Fibromyalgia Patients by Symptom Incidence, Severity May Improve Treatment Outcomes
Although fibromyalgia lacks an effective standardized treatment, one part of the problem is the condition's diverse constellation of symptoms that include chronic widespread pain, fatigue, and even depression.