Uveitis

Researchers evaluated children with arthritis, uveitis, and both.

When standard treatment failed, adding adalimumab achieved remission in 64%.

A combination of mycophenolate mofetil and corticosteroid showed benefit.

People with noninfectious uveitis tend to have low vitamin D levels.

Elevated IOP is uncommon in uveitis, but showed up in a pair of Zika patients.

Report underscores the need to act quickly, refer patients with eye problems.

Evidence of the correlation is strong, but the exact cause remains unverified.

T. gondii is one of the most common causes of infectious posterior uveitis.

An association is logical: nerve and eye tissue develop from the same cells.

Understanding the cytokine’s role may be valuable in diagnosis and treatment.

A 12-tube polymerase chain reaction strip can detect 24 ocular pathogens.

Annual rate of ocular inflammatory flares fell from 200 to 49 per 100 patients.

Monitoring Zika-exposed patients for visual symptoms and ocular findings is particularly important because these may be the only indicators of the infection in some patients.

Some cases of tubulointerstitial nephritis and uveitis syndrome, or TINU, have a poor visual prognosis, so early diagnosis and treatment are recommended. Diagnosis requires detailed history taking, whole-body imaging studies, and examination of renal function.

In the SAKURA study, a greater proportion of those in the intravitreal sirolimus treatment groups than those in the active control group met the primary endpoint, a vitreous haze score of zero at Month 5 without the use of rescue therapy.

A retrospective review of patients with bilateral uveitic glaucoma who had filtration surgery in both eyes at different times found that the second surgically treated eye showed greater glaucomatous disc progression than the first.

A Spanish research team found an association between testing positive for antibodies to adalimumab (Humira) and a worse outcome of uveitis, but only in those who tested positive permanently. They also found that this association correlated with undetectable trough levels of Humira.

Most patients with severe refractory juvenile ideiopathic arthritis-associated uveitis may get complete remission after six months of treatment with tocilizumab (Actemra/Roche.)

Santen Pharmaceutical Co., Ltd. today announced topline results from a phase 3 trial of Opsiria, a sirolimus injection intended to treat non-infectious posterior uveitis.

Patients with intermediate uveitis (IU) have a high likelihood of achieving good long-term visual outcomes, but should expect a long disease course and frequent complications

Researchers concerned about inconsistencies in rating disease activity in uveitis have come up with a new scoring system called UVEDAI.

Adalimumab has the potential to serve an important role in management of chronic and refractory noninfectious uveitis and associated macular edema with low rates of serious adverse events in the long term, according to a recent report. That includes pediatric patients.

Cytomegalovirus or CMV’s an etiological factor in patients with hypertensive anterior uveitis in Korea, according to a recent study.

Noninfectious uveitis (NIU) is more prevalent among female than male adults and the number of cases increase in tandem with age, according to a recent study.

Adalimumab (ADA) works well as a treatment for patients with both active and inactive uveitis whether or not they are taking an immunosuppressant (IMM); however, the median time to treatment failure (mTTF) is longer for patients with inactive uveitis taking an IMM.

Panuveitis is associated with recurrent or persistent inflammation (R/PI) for patients with both active and inactive uveitis, a study found.

Medical technology is constantly evolving across fields, and ophthalmology is no exception. A new hypersonic vitrectomy device is currently in development and could be on the market in 2017.

A new study out of Ireland examined the prevalence of extra-articular manifestations in axial spondyloarthritis, and found that women were at significantly higher risk for inflammatory bowel disease and uveitis than men.

The prevalence of noninfectious uveitis was 121 cases per 100,000 adults and 29 cases per 100,000 children. By such estimates, nearly 300,000 adults and 22,000 children in the United States had the disease in 2015.

Before antibiotics, people went blind from syphilis. They still could, the US Centers for Disease Control and Prevention warned today.