The HCPLive Gastroenterology condition center page is a comprehensive resource for clinical news and insights on digestive and GI conditions. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for C difficile, IBS and IBD, Crohn's disease, and more.
November 22nd 2024
The supplemental Biologics License Application is supported by the phase 3 ASTRO study of guselkumab SC induction therapy in ulcerative colitis.
Inherited Gut Bacteria Drives Crohn's Disease and Ulcerative Colitis
A team of researchers recently reported that human genes may partially influence intestinal bacteria spurring inflammatory bowel disease (IBD) conditions like Crohn's disease (CD) and ulcerative colitis (UC).
Study Shows Hepatitis C Doesn't Cause Mental Impairment in HIV Coinfected Patients
December 18th 2014Hepatitis C does not contribute to mental impairment in patients who are coinfected with HIV when there is an absence of substantial liver damage, according to a study published online in the journal Neurology.
Hidden Key to Treating Nonalcoholic Fatty Liver Disease
An international team of researchers recently reported that inhibiting a nuclear receptor in the gut could spur favorable treatment for nonalcoholic fatty liver disease (NAFLD), in which buildup of fat in liver cells disrupts liver function.
Changing Clinical Notes Through Electronic Health Records
As electronic health records become more or less mandatory, the question moves from how widely they are adopted by practices across the country to whether the new versions are more effective than the old pen-and-paper way of doing business.
AbbVie Gets Closer to EU Approval of New Hepatitis C Drug
December 5th 2014A committee for the European Medicines Agency has recommended approval for a hepatitis C drug combination, a key step to winning European marketing authorization for the drug maker AbbVie. The recommendation for marketing authorization is for AbbVie's investigational drug named Exviera (dasabuvir) and Viekirax (ombitasvir, paritaprevir and ritonavir) for the treatment of chronic hepatitis C virus infection in combination with other medicine.
FDA Letter Stalls Bristol-Myers Squibb's Hepatitis C Drug Application
December 5th 2014The US Food and Drug Administration recently rejected a bid by Bristol-Myers Squibb to win regulatory approval for its hepatitis C drug daclatasvir, pending further information requested in a Complete Response Letter issued by the agency.
Comorbidity Identified Between Bowel and Lung Diseases
December 4th 2014Individuals with airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) are more likely to be diagnosed with inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, a new study published in the European Respiratory Journal suggested.
Gastroenterologists Consider Novel Procedure of POEM
Although the introduction of peroral endoscopic myotomy (POEM) for the treatment of achalasia, a condition that affects the ability of the esophagus to move food into the stomach, has caused quite a stir, clinicians are reminded to consider additional factors when discussing therapeutic options.
Triple Therapy for Hepatitis C Infection: Bacterial Infection Risk Rises, Changes
December 1st 2014Patients who have HCV infection are at high risk for arthralgia, myalgias, pruritus, neuropathy, and decompensated livers. Until recently the sole available treatment was interferon. After the US Food and Drug Administration (FDA) approved ribavirin, patients who took ribavirin plus interferon responded better. Now, the FDA has approved a small selection of oral antivirals to treat hepatitis C.
Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome
Modifying diet is one way to try to help patients with Irritable Bowel Syndrome (IBS). In a study reported in Gastroenterology, an Australian research team looked at the effects of lowering fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) vs. consuming a typical Australian diet.
Non-invasive Colon Cancer Screen Effective
More than 23 million Americans who should be screened for colon cancer have not yet been screened. To the extent that lapse is due to patients' reluctance to submit to a colonoscopy, a non-invasive stool test could help – if it is effective. A research team looked at such a test, one made by Exact Sciences Corp. and approved in November, 2014 for Medicare reimbursement.
COPD, Asthma May Increase Risk for Inflammatory Bowel Disease
Study results published in the European Respiratory Journal show that rates of inflammatory bowel disease (IBD) incidence have significantly increased in individuals with asthma or chronic obstructive pulmonary disease (COPD).
Advanced Colorectal Cancer: 3 Drugs Are Better Than One
Patients with advanced colorectal cancer previously only had access to limited treatment options; however, new research presented at the 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain, indicated a combination of 3 targeted drugs could potentially serve as a successful treatment.
Hopeful Study Results for Patients with Cirrhosis and Hepatitis C
November 21st 2014Patients with cirrhosis who took part in a study that tested a triple combination drug for hepatitis C with ribavirin saw normalization of key laboratory tests after three and six month treatment periods, an indication of improved liver condition.
Readmission Penalties and Their Affect on Patient Care
As hospitals around the country deal with the newly instituted readmission penalties many are having to look at how they will handle providing the same level of care without some of the money they counted on in the past.
Understanding ANCA-Associated Vasculitis
Affecting just one in every 100,000 people, ANCA-associated vasculitis is not one of the more common conditions nephrologists will encounter. However, without proper treatment it can have serious adverse effects on a patient's life.