IgA nephropathy diagnosis involves clinical evaluation, laboratory tests, and renal biopsy to differentiate from similar glomerular diseases.
Renal biopsy with immunofluorescence microscopy is crucial, revealing mesangial IgA deposits specific to IgAN.
Lupus nephritis shows full-house immunofluorescence staining, while membranous nephropathy has subepithelial immune deposits.
Accurate differentiation is essential for appropriate disease management and treatment strategies.
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Panelists discuss how clinicians can differentiate IgA nephropathy from other glomerular diseases, such as lupus nephritis and membranous nephropathy, that may present with similar clinical features.
How do clinicians differentiate IgANIgA nephropathy from other glomerular diseases, such as lupus nephritis or membranous nephropathy, which can present with similar clinical features?