Safety of IgAN Treatments

Author(s):

Jonathan Barratt, PhD, FRCP,Anuja Java, MD

Key Takeaways

Biomarkers, including genetic mutations and protein expressions, are vital for predicting disease progression and treatment response.
Advanced diagnostic techniques are essential for identifying molecular and cellular indicators that inform patient prognosis.
Clinical indicators like tumor size, stage, and overall health status are crucial in assessing disease outcomes.
Personalized medicine utilizes biomarkers to customize treatment plans, improving therapeutic efficacy and patient survival.

Panelists discuss how adverse effects associated with corticosteroids can significantly affect patient adherence and quality of life, emphasizing the need for future therapies to strike a balance between efficacy and a more tolerable adverse effect profile.

EP: 1.Overview of IgAN and Its Common Symptoms

EP: 2.IgAN Progression

EP: 3.IgAN vs Other Glomerular Diseases

EP: 4.Biomarkers for IgAN

EP: 5.Genetic Screening for IgAN

EP: 6.Impact of IgAN on Quality of Life

EP: 7.Misdiagnosis and Barriers to Early Detection of IgAN

EP: 8.Differential Diagnoses of IgAN

EP: 9.Significance of Proteinuria for Potential IgAN

EP: 10.Proteinuria Variability and IgAN Diagnosis

EP: 11.Biomarkers and Improving IgAN Diagnostic Accuracy

EP: 12.Primary Treatment Goals for Patients With IgAN

EP: 13.Proteinuria Reduction in Long-Term Kidney Damage Prevention

EP: 14.Symptoms Management and Targeting the Root Cause of IgAN

EP: 15.Unmet Needs in Current IgAN Treatment

EP: 16.Prospective Improvements of Existing IgAN Therapies

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EP: 17.Safety of IgAN Treatments

How do adverse effects, such as those associated with corticosteroids, affect patient adherence and quality of life? How should future therapies aim to balance efficacy with a more tolerable adverse effect profile?