Opinion

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Seladelpar for Treatment of PBC

Key Takeaways

  • Seladelpar demonstrates sustained efficacy in improving liver biochemistry and symptom relief in primary biliary cholangitis (PBC) over long-term use.
  • The drug modulates lipid metabolism and inflammation, crucial mechanisms in managing PBC, enhancing its therapeutic potential.
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The panel of experts review the long-term data on the recently FDA-approved PPAR-δ agonist seladelpar for primary biliary cholangitis (PBC), focusing on its efficacy, safety, and impact on liver biochemistry markers over time.

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