Opinion

Video

Thoughts on the Current State of PBC Management

Key Takeaways

  • PBC involves autoimmune-mediated destruction of intrahepatic bile ducts by autoreactive T lymphocytes, leading to cholestasis.
  • Accumulation of toxic bile acids due to cholestasis causes hepatocellular damage and inflammation.
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The panel of experts offers expert insights and concluding thoughts on the management of primary biliary cholangitis (PBC), emphasizing the importance of personalized treatment strategies, monitoring, and the evolving role of new therapies in improving patient outcomes.

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