Chronic Pain

Dr Daniel J. Clauw provides an overview of pharmacologic and nonpharmacologic therapeutic approaches for the management of fibromyalgia and comments on challenges and unmet needs for patients.

Daniel J. Clauw, MD, describes the role the brain and CNS play in controlling the setting of nociplastic pain in patients with fibromyalgia and highlights increased patient sensitivity to sensory stimuli.

An international review of data show certain antidepressants may benefit conditions like fibromyalgia, but many trials are actually inconclusive.

“The fact that patients report substituting cannabis for pain medications so much underscores the need for research on the benefits and risk of using cannabis for chronic pain,” investigators stated.

Neither intervention group demonstrated any significant improvements in intensity of chronic breathlessness after taking regular, low-dose, extended-release morphine.

Reductions in prescribed benzodiazepines were especially noted in continuing prescriptions.

New comparative effectiveness data go against CDC recommendations for tapering or abruptly ending long-term opioid prescription.

FDA approved combination therapy relugolix, estradiol, and norethindrone acetate (Myfembree) for the management of moderate to severe pain associated with endometriosis.

After March 2020, overdose deaths not involving methadone continued to increase whereas methadone-involved overdose deaths remained stable.

According to a new report from the CDC, as fatal drug overdoses increase across the board, the Black and Indigenous communities represent a significantly greater death rates.

An Ohio State researcher discusses a new medical center education program for navigating addiction risk in pain patients.

During the analysis, investigators became fascinated by how many patients entered the buprenorphine treatment program for OUD having already been taking the drug without a prescription.

Data indicate that higher levels of perceived pain related disability and greater difficulty falling asleep was associated with increased anxiety levels in adults with fibromyalgia and insomnia.

Since the delivery of these medications were disrupted during the pandemic, members of racial and ethnic minority groups experienced an increased risk of opioid overdose, compared with White individuals.

Presence of chronic liver disease, prior use of gabapentin and being discharged to a long-term hospital or rehabilitation center are among some of the factors associated with a new opioid use disorder diagnosis.

The daily oral combination therapy will be reconsidered for treating endometriosis pain this August.

Emergency medicine specialist urges hospitals to add methylnaltrexone to the hospital formulary after promising research shows the treatment's success with opioid-induced constipation.

methylnaltrexone is more effective, less costly, and can even keep some patients out of the hospital after being treated for opioid-induced constipation in the emergency department.

A new method of opioid disposal was proposed by the FDA in an attempt to mitigate unauthorized access to opioids and lessen risk of addiction.

Acadia Pharmaceuticals evaluated the effects of its novel redox modulator drug on pain intensity levels of patients undergoing a bunionectomy.

The NaV1.8 inhibitor VX-548 shows promising potential as a non-opioid acute pain treatment.

Patients with psoriatic arthritis and ankylosing spondylitis experienced rapid pain reduction with upadacitinib, regardless of treatment history.

From the struggle of obtaining insurance approvals to addressing the nationwide shortage of rheumatologists, Dr. Baker Frost talks about her experience treating patients with autoimmune disease.

The Director of Policy and Advocacy for the US Pain Foundation addresses the important changes made to the updated draft of the CDC Clinical Practical Guideline for Prescribing Opioids 2022.

A summarization of the in-depth review, editorial and synopsis provided by multiple experts after revising the updates to the VA/DoD joint clinical practice guideline for substance use disorders.

The use and legalization of cannabis products has been increasing in the US for a variety of medical concerns. Investigators aim to better understand the risks and benefits of owning a medical marijuana card.

Mindfulness-oriented recovery enhancement is unlike other mindfulness-based treatments and was found superior to supportive group psychotherapy for treating opioid misuse and chronic pain.

When the pandemic began, prescribers in Canada were allowed to increase the amount of opioid agonist therapy take-home doses for individuals with opioid use disorder.

Why is Rare Disease Day so important? Hear the answers from some of the most qualified professionals in rare disease fields.