Insomnia

Announced on May 29, 2024, data from the MDD3001 trial indicate use of seltorexant was associated with meaningful improvements in depressive symptoms and sleep disturbances.

With limited CBTi-trained psychologists, investigators assessed the effectiveness of a self-guided digital CBTi as another option, so people don’t have to turn to pills.

More than half of the participants were identified as insomnia sleepers and nappers, two suboptimal sleep patterns linked with an increased risk of a chronic condition.

FDA issued a Complete Response Letter to Vanda Pharmaceuticals stating tasimelteon for treating insomnia cannot be approved in its current form due to identified deficiencies.

A new study found non-hospitalized COVID-19 survivors from a Vietnam general population had a 76.1% prevalence of insomnia, with 22.8% of respondents with insomnia scoring for severe insomnia.

Male college students were found to consume more energy drinks than female college students, and they had a greater risk for a short sleep duration due to energy drink consumption.

A new study found critical components of CBT-I are cognitive restructuring, third-wave components, sleep restrictions, and stimulus control.

Investigators observed no change in Insomnia Severity Index scores from baseline to weeks 7 and 25 with CBT-1, trazodone, or placebo, suggesting these insomnia treatment options are not effective for patients undergoing hemodialysis.

A new study found patients who scored high on the Insomnia Severity Index questionnaire had a longer hospital stay length, increased risk of 30-day readmission, and increased risk of 30-day emergency department or urgent care visits.

A nationwide Taiwan-based study found benzodiazepine use during pregnancy was linked to roughly a 70% increased risk of miscarriage.

Late shift work is associated with sleep disorders the most for females, the age group <30 years old, people who live alone or with roommates, have only up to an elementary or secondary education, and people who work the night shift.

In the second index, REM fragmentation decreased more in the SRT group than the control group, but in other indexes, there was not a statistical difference.

A proof-of-concept trial shows a program that addresses sleep pressure, circadian rhythm and hyperarousal in adolescents and young adults receiving mental health care is promising.

Results show 60% of the children with FASD experienced nightmares, while 44% exhibited frequent insomnia symptoms.

Investigators systematically review data to further understand the relationship between sleep and PTSD as it impacts treatment outcomes.

Reports from the intervention group show decreased alcohol-related problems, mediated by the change in insomnia severity following treatment.

Experiencing everyday discrimination is a significant predictor of sleep-related impairments among Black adults, highlighting the detrimental impact of discrimination.

“Our findings underline the importance of sleep health in treating depression as the nation battles the current mental health crisis,” investigators write.

“These results have significant implications for the scalability of circadian medicine, particularly as consumer-based wearable technology is already commonplace,” investigators explain.

Higher levels of hydrocinnamate and indolepropionate were associated with lower WHIIRS, with stronger associations found in female participants.

The rate of sleep apnea is greater in patients with bipolar disorder and depression.

Depression is linked with an increased incidence of multiple nonoverlapping physical conditions requiring hospital treatment, including endocrine, musculoskeletal, and vascular diseases.

Clozapine treatment may offer the added benefit of improved sleep in patients with schizophrenia, according to a meta-analysis.

This marks the first and only FDA-approved once-at-bedtime oxybate for individuals living with narcolepsy.

According to the study, gay and bisexual adolescents show higher rates of sleep issues and sleep disturbances.