Epilepsy

The once-daily oral therapy is recommended at a 200 mg dose, following titration.

Children exposed in utero to valproate were most affected, but exposure to 3 other monotherapies were also associated with behavioral issues.

FDA approved midazolam nasal spray for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity distinct from a patient's usual seizure pattern in patients with epilepsy 12 years of age and older.

How can emergency department doctors best be prepared to identify and treat seizures in the ER?

Investigators studied patients from 5 unrelated families to determine the genetic mutations causing the condition.

Research into a rare neurological disorder may help researchers working on more common diseases including autism and epilepsy.

Characterizing these pediatric epilepsy readmissions is the first step in reducing readmissions, study authors said.

Results suggest that pediatric patients with epilepsy should have genomic test results reinterpreted at least every 2 years and before further genetic testing.

A cross-validated, stratified cohort found that certain epilepsy patient populations could be at a two-fold greater risk of AED-related psychiatric effects.

Largest observational study on antiepileptic treatment for poststroke epilepsy finds highest adherence to a less frequently prescribed drug.

Investigators found atypical responses from brain cells known as astrocytes, which follow traumatic brain injuries (TBIs), may be the cause of epilepsy development.

A delay in giving the first dose of an antiepileptic for pediatric status epilepticus is common and associated with increased seizure duration.